Tip: Instead of targeting large keywords (with lots of monthly searches) in one main article – try targeting lots of long tail keywords in lots of different articles. I’ve been having success with this strategy for a long time now – and more recently Spencer and his team at Niche Pursuits have been using this strategy and talking extensively about it.
The keywords you want to focus your SEO on should closely resemble the vocabulary of your audience. In order to come up with the proper keywords you really have to get inside the heads of the people who search for your website. What terms will people use? How do people search? Which question does your website answer? You should create a list of all search terms people could use and think of combinations and nuances within these search terms.

1 – I’ve found a niche with low competition and good CPC . but the thing is the while doing competition analysis. I observed that most of the sites that are in the top 10 serps ranking are small ecommerce site selling their own product or sites like niche specific classified ad site with low and thin content. What are your suggestions ? Should I go for such keywords ?
Long Tail Pro is a keyword research tool that helps you quickly find low competition keywords for your website.  In particular, the tool is built for people doing SEO (search engine optimization) as opposed to people doing paid ads (Google Adwords PPC).  I'm sure there are some advertisers that use the tool for paid ad keyword research, but the tool was built for SEO keyword research.
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